Enzyme Catalysis

Illustrative Examples
    Protein Tyrosine Phosphatases
    Cathepsin K
    Phosphotriesterase (PTE)
    Alanine Racemase    
              Carbon Acidity
    Haloalkane Dehalogenase
              Mechanism and Kinetic Isotope Effect 
              Dynamics and Mechanism
    4-Oxalocrotonate Tautomerase
    Hairpin Ribozyme
    Nitroalkane Oxidase
    Dopa Decarboxylase
    Aristolochene Synthase
    Dihydrofolate Reductase (DHFR)
              Temperature dependence KIE
              Reaction Path and Mechanism
              Nature of Transition State
              KIE in Hyperthermophilic DHFR
    Squalene Cyclase
    4-Chlorobenzoyl-CoA dehalogenase
    Acyl-CoA Dehydrogenase
              Free Energy Surface, Reaction Paths, and KIE
              Potential of Mean Force and Effects of Mutations
    Liver alcohol dehydrogenase
              Quantum Dynamics of Hydride Transfer
              Canonical Variational Theory, Quantum Mechanical Tunneling Dynamics
    Xylose Isomerase
    Carbonic Anhydrase
    HIV-1 Protease